There are 80 species of mammals, 280 species of Birds, 100 species of Butterflies, 26 species of spiders, 30 species of Reptiles (including 25 species of snakes), 5 species of Amphibians, 23 species of Fishes recorded from the Reserve.  The common Avifauna of 280 species recorded includes 50 species of migratory birds and 158 species of resident birds.  One remarkable bird, Bar-headed Goose, which is a winter visitor from Ladakh and Tibet inhabits Chargaon and Sitarampeth tanks which are adjoining the Protected Area.  In March/2002, 22 Bar Headed geese were seen in the Tadoba Lake for about 10 days.
Tiger, Leopard, Sloth Bear, Gaur or Indian Bison, Barking Deer, Spotted Deer, Sambar, Wild Boar, Four-Horned Antelope, Wild Dog , Langoor, Nilgai, Marsh Crocodile are commonly sighted in the Tiger Reserve by the tourists.
Ratel, Flying Squirrel, Palm Civet, Indian Civet, Leopard Cat, Rusty Spotted Cat, Pangolin and Jackal are also reported.